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Applied BioMath Assess™
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Applied BioMath Assess™
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Case Studies
Case Studies
Using Assess to Predict Doses and Align Stakeholders
Avidity for Safe and Efficacious Bispecifics
Early Dose Projections of a HER2 Targeting Antibody
Dose Feasibility of LNP-delivered mRNA Therapeutics
Receptor-Ligand Inhibition for Checkpoint Inhibitors
On-Target, Off-Tumor Toxicity of Solitomab
Using Assess
Using Assess
Scenarios
Basic Operations
Exporting Results
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General Model Mechanisms
General Model Mechanisms
Drug Mechanisms
Protein Mechanisms
Multi-Compartment Models
Binding Reactions
Model Parameters
Model Parameters
ADC Deconjugation Half-life
Avidity Chi Factor
Distribution Half-life
Dose
Drug to Antibody Ratio
Drug Half-life
Drug:Target Affinity
Ligand Concentration
Ligand Half-life
Ligand Receptor Affinity
Molecular Weight
Number Cells
Partition Coefficient
Receptor Concentration
Receptor Half-life
Soluble Receptor Concentration
Soluble Receptor Half-life
Valency
Volume, Central
Volume, Distribution
Volume, Peripheral
Volume, Tox
Volume, Disease
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